Epigenetics

With long-read SMRT Sequencing, you can perform epigenetic characterization to achieve a more complete view of microbial and eukaryotic DNA modifications.

Characterize the epigenetic landscape of your genome

Single Molecule, Real-Time (SMRT) Sequencing directly detects epigenetic modifications by measuring kinetic variation during base incorporation. By capturing these modifications simultaneously with sequence data, this method eliminates the need for special sample preparation and additional sequencing.

 

PacBio Sequencing provide a direct view of epigenetic modification

  • Characterize bacterial DNA modifications and methyltransferase recognition motifs
  • Identify eukaryotic hyper- and hypo-methylated CpG islands to explore gene expression and regulation

Epigenetics Application Brochure –  Characterize the epigenetic landscape of your genome

To learn more about how SMRT Sequencing simultaneously captures genomic and epigenetic information, contact us.